Free Download Pharmaceutical Organic Chemistry 2 Notes in pdf – Bpharm 3rd Semester. High quality, well-structured and Standard Notes.
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In this post you can download notes of Pharmaceutical Organic Chemistry 2 (BP301T). All units are available to download for free.
Pharmaceutical Organic Chemistry 2 Notes pdf
UNIT – 1
Benzene and its derivatives
UNIT – 2
Aromatic Acids, Aromatic Amines, Phenols
UNIT – 3
Fats and Oils
UNIT – 4
Polynuclear hydrocarbons (Naphthalene, Anthracene, Phenanthrene, Diphenyl Methane, Triphenyl Methane)
UNIT – 5
Cyclo alkanes
Syllabus of Pharmaceutical Organic Chemistry
UNIT – 1
Benzene and its derivatives
A. Analytical, synthetic and other evidences in the derivation of structure
of benzene, Orbital picture, resonance in benzene, aromatic
characters, Huckel’s rule
B. Reactions of benzene – nitration, sulphonation, halogenationreactivity, Friedelcrafts alkylation- reactivity, limitations,
Friedelcrafts acylation.
C. Substituents, effect of substituents on reactivity and orientation of
mono substituted benzene compounds towards electrophilic
substitution reaction
D. Structure and uses of DDT, Saccharin, BHC and Chloramine
UNIT – 2
Phenols* – Acidity of phenols, effect of substituents on acidity, qualitative
tests, Structure and uses of phenol, cresols, resorcinol, naphthols
Aromatic Amines* – Basicity of amines, effect of substituents on basicity, and synthetic uses of aryl diazonium salts
Aromatic Acids* – Acidity, effect of substituents on acidity and
important reactions of benzoic acid.
UNIT – 3
Fats and Oils
a. Fatty acids – reactions.
b. Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying
oils.
c. Analytical constants – Acid value, Saponification value, Ester value,
Iodine value, Acetyl value, Reichert Meissl (RM) value – significance and
principle involved in their determination.
UNIT – 4
Polynuclear hydrocarbons:
a. Synthesis, reactions
b. Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane, Triphenylmethane and their derivatives
UNIT – 5
Cyclo alkanes*
Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory, Coulson and Moffitt’s modification, Sachse Mohr’s theory (Theory of strainless rings), reactions of cyclopropane and cyclobutane only
Scope of Pharmaceutical Organic Chemistry
This subject deals with general methods of preparation and reactions of some
organic compounds. Reactivity of organic compounds are also studied here. The syllabus
emphasizes on mechanisms and orientation of reactions. Chemistry of fats and oils are
also included in the syllabus.
Objectives of Pharmaceutical Organic Chemistry
Upon completion of the course the student shall be able to:
- Write the structure, name and the type of isomerism of the organic compound.
- Write the reaction, name the reaction and orientation of reactions.
- Account for reactivity/stability of compounds.
- Prepare organic compounds.