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Bpharm 6th-Semester Notes

Download Bpharm 6th-Semester Notes in pdf

MEDICINAL CHEMISTRY – III

This subject is designed to impart fundamental knowledge on the structure, chemistry and therapeutic value of drugs.

UNIT 1

Antibiotics, β-Lactam antibiotics, Aminoglycosides, Tetracyclines

UNIT 2

Antibiotics, Macrolide, Miscellaneous, Prodrugs, Antimalarials, Quinolines, Biguanides and dihydro triazines, Miscellaneous

UNIT 3

Anti-tubercular Agents, Synthetic anti tubercular agent, Anti tubercular antibiotics, Urinary tract anti-infective agent, Quinolones, Miscellaneous, Antiviral agents

UNIT 4

Antifungal agents, Antifungal antibiotics, Synthetic Antifungal agents, Anti-protozoal Agents, Anthelmintics, Sulphonamides and Sulfones, Folate reductase inhibitors, Sulfones

UNIT 5

Introduction to Drug Design, Combinatorial Chemistry

PHARMACOLOGY-III

This subject is intended to impart the fundamental knowledge on various aspects (classification, mechanism of action, therapeutic effects, clinical uses, side effects and contraindications) of drugs acting on respiratory and gastrointestinal system, infectious diseases, immunopharmacology, and in addition,emphasis on the principles of toxicology and chronopharmacology.

UNIT 1

Pharmacology of drugs acting on Respiratory system, Pharmacology of drugs acting on the Gastrointestinal Tract

UNIT 2

Chemotherapy, Sulfonamides and cotrimoxazole, Antibiotics

UNIT 3

Chemotherapy – Antitubercular agents, Antileprotic agents, Antifungal agents, Antiviral drugs, Anthelmintics, Antimalarial drugs, Antiamoebic agent

UNIT 4

Urinary tract infections and sexually transmitted diseases, Chemotherapy of malignancy, Immunopharmacology

UNIT 5

Principles of toxicology, Chronopharmacology

HERBAL DRUG TECHNOLOGY

This subject gives the student the knowledge of basic understanding of herbal drug industry, the quality of raw material, guidelines for quality of herbal drugs, herbal cosmetics, natural sweeteners, nutraceutical etc. The subject also emphasizes on Good Manufacturing Practices (GMP), patenting and regulatory issues of herbal drugs.

UNIT 1

Herbs as raw materials, Biodynamic Agriculture, Indian Systems of Medicine

UNIT 2

Nutraceuticals, Herbal-Drug and Herb-Food Interactions

UNIT 3

Herbal Cosmetics, Herbal excipients, Herbal formulations

UNIT 4

Evaluation of Drugs, Patenting and Regulatory requirements of natural products, Regulatory Issues

UNIT 5

General Introduction to Herbal Industry, Schedule T – Good Manufacturing Practice of Indian systems of medicine

BIOPHARMACEUTICS AND PHARMACOKINETICS

This subject is designed to impart knowledge and skills of Biopharmaceutics and pharmacokinetics and their applications in pharmaceutical development, design of dose and dosage regimen and in solving the problems arised therein.

UNIT 1

Introduction to Biopharmaceutics, Absorption, Distribution

UNIT 2

Elimination, Bioavailability and Bioequivalence

UNIT 3

Pharmacokinetics

UNIT 4

Multicompartment models

UNIT 5

Nonlinear Pharmacokinetics

PHARMACEUTICAL BIOTECHNOLOGY

UNIT 1

Introduction to Biotechnology, Enzyme Biotechnology, Biosensors, Brief introduction to Protein Engineering, Use of microbes in industry & Production of Enzymes, basic principles of genetic engineering

UNIT 2

Study of cloning vectors, Recombinant DNA technology, Application of r DNA technology and genetic engineering, Brief introduction to PCR

UNIT 3

Types of immunity, Immunoglobulins, MHC, Hypersensitivity reactions, Preparation of Bacterial Vaccine, Storage conditions and stability of official vaccines, Hybridoma technology, Blood products and Plasma Substituties

UNIT 4

Immuno blotting techniques, Genetic organization of Eukaryotes and Prokaryotes, Microbial genetics, Microbial biotransformation and applications, Mutation

UNIT 5

Fermentation, Large scale production fermenter design, Study of the production, Blood Products

PHARMACEUTICAL QUALITY ASSURANCE

This course deals with the various aspects of quality control and quality assurance aspects of pharmaceutical industries.

UNIT 1

Quality Assurance and Quality Management concepts, Total Quality Management (TQM), ICH Guidelines, Quality by design (QbD), ISO 9000 and ISO14000, NABL accreditation

UNIT 2

Organization and personnel, Premises, Equipments and raw materials,

UNIT 3

Quality Control and Good Laboratory Practices

UNIT 4

Complaints and document maintenance in pharmaceutical industry

UNIT 5

Calibration and Validation, Warehousing

Bpharm 6th Semester Subject Scope :

Scope of Medicinal Chemistry 3 : This subject is designed to impart fundamental knowledge on the structure, chemistry and therapeutic value of drugs. The subject emphasis on modern techniques of rational drug design like quantitative structure activity relationship (QSAR), Prodrug concept, combinatorial chemistry and Computer aided drug design (CADD). The subject also emphasizes on the chemistry, mechanism of action, metabolism, adverse effects, Structure Activity Relationships (SAR), therapeutic uses and synthesis of important drugs.

Scope of Pharmacology 3 : This subject is intended to impart the fundamental knowledge on various aspects (classification, mechanism of action, therapeutic effects, clinical uses, side effects and contraindications) of drugs acting on respiratory and gastrointestinal system, infectious diseases, immuno-pharmacology and in addition,emphasis on the principles of toxicology and chronopharmacology.

Scope of Herbal Drug Technology : This subject gives the student the knowledge of basic understanding of herbal drug industry, the quality of raw material, guidelines for quality of herbal drugs, herbal cosmetics, natural sweeteners, nutraceutical etc. The subject also emphasizes on Good Manufacturing Practices (GMP), patenting and regulatory issues of herbal drugs.Add Image

Scope of Biopharmaceutics and Pharmacokinetics : This subject is designed to impart knowledge and skills of Biopharmaceutics and pharmacokinetics and their applications in pharmaceutical development, design of dose and dosage regimen and in solving the problems arised therein.Add Image

Scope of Pharmaceutical Biotechnology : has a long promise to revolutionize the biological sciences and technology. Scientific application of biotechnology in the field of genetic engineering, medicine and fermentation technology makes the subject interesting. Biotechnology is leading to new biological revolutions in diagnosis, prevention and cure of diseases, new and cheaper pharmaceutical drugs. Biotechnology has already produced transgenic crops and animals and the future promises lot more. It is basically a research-based subject.Add Image

Scope of Pharmaceutical Quality Assurance : This course deals with the various aspects of quality control and quality assurance aspects of pharmaceutical industries. It deals with the important aspects like cGMP, QC tests, documentation, quality certifications and regulatory affairs.

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