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Bpharm 6th Semester Notes:
- Medicinal Chemistry 3
- Pharmacology 3
- Herbal Drug Technology
- Biopharmaceutics and Pharmacokinetics
- Pharmaceutical Biotechnology
- Pharmaceutical Quality Assurance
Download Bpharm 6th-Semester Notes in pdf
MEDICINAL CHEMISTRY – III
This subject is designed to impart fundamental knowledge on the structure, chemistry and therapeutic value of drugs.
UNIT 1
Antibiotics, β-Lactam antibiotics, Aminoglycosides, Tetracyclines
UNIT 2
Antibiotics, Macrolide, Miscellaneous, Prodrugs, Antimalarials, Quinolines, Biguanides and dihydro triazines, Miscellaneous
UNIT 3
Anti-tubercular Agents, Synthetic anti tubercular agent, Anti tubercular antibiotics, Urinary tract anti-infective agent, Quinolones, Miscellaneous, Antiviral agents
UNIT 4
Antifungal agents, Antifungal antibiotics, Synthetic Antifungal agents, Anti-protozoal Agents, Anthelmintics, Sulphonamides and Sulfones, Folate reductase inhibitors, Sulfones
UNIT 5
Introduction to Drug Design, Combinatorial Chemistry
PHARMACOLOGY-III
This subject is intended to impart the fundamental knowledge on various aspects (classification, mechanism of action, therapeutic effects, clinical uses, side effects and contraindications) of drugs acting on respiratory and gastrointestinal system, infectious diseases, immunopharmacology, and in addition,emphasis on the principles of toxicology and chronopharmacology.
UNIT 1
Pharmacology of drugs acting on Respiratory system, Pharmacology of drugs acting on the Gastrointestinal Tract
UNIT 2
Chemotherapy, Sulfonamides and cotrimoxazole, Antibiotics
UNIT 3
Chemotherapy – Antitubercular agents, Antileprotic agents, Antifungal agents, Antiviral drugs, Anthelmintics, Antimalarial drugs, Antiamoebic agent
UNIT 4
Urinary tract infections and sexually transmitted diseases, Chemotherapy of malignancy, Immunopharmacology
UNIT 5
Principles of toxicology, Chronopharmacology
HERBAL DRUG TECHNOLOGY
This subject gives the student the knowledge of basic understanding of herbal drug industry, the quality of raw material, guidelines for quality of herbal drugs, herbal cosmetics, natural sweeteners, nutraceutical etc. The subject also emphasizes on Good Manufacturing Practices (GMP), patenting and regulatory issues of herbal drugs.
UNIT 1
Herbs as raw materials, Biodynamic Agriculture, Indian Systems of Medicine
UNIT 2
Nutraceuticals, Herbal-Drug and Herb-Food Interactions
UNIT 3
Herbal Cosmetics, Herbal excipients, Herbal formulations
UNIT 4
Evaluation of Drugs, Patenting and Regulatory requirements of natural products, Regulatory Issues
UNIT 5
General Introduction to Herbal Industry, Schedule T – Good Manufacturing Practice of Indian systems of medicine
BIOPHARMACEUTICS AND PHARMACOKINETICS
This subject is designed to impart knowledge and skills of Biopharmaceutics and pharmacokinetics and their applications in pharmaceutical development, design of dose and dosage regimen and in solving the problems arised therein.
UNIT 1
Introduction to Biopharmaceutics, Absorption, Distribution
UNIT 2
Elimination, Bioavailability and Bioequivalence
UNIT 3
Pharmacokinetics
UNIT 4
Multicompartment models
UNIT 5
Nonlinear Pharmacokinetics
PHARMACEUTICAL BIOTECHNOLOGY
UNIT 1
Introduction to Biotechnology, Enzyme Biotechnology, Biosensors, Brief introduction to Protein Engineering, Use of microbes in industry & Production of Enzymes, basic principles of genetic engineering
UNIT 2
Study of cloning vectors, Recombinant DNA technology, Application of r DNA technology and genetic engineering, Brief introduction to PCR
UNIT 3
Types of immunity, Immunoglobulins, MHC, Hypersensitivity reactions, Preparation of Bacterial Vaccine, Storage conditions and stability of official vaccines, Hybridoma technology, Blood products and Plasma Substituties
UNIT 4
Immuno blotting techniques, Genetic organization of Eukaryotes and Prokaryotes, Microbial genetics, Microbial biotransformation and applications, Mutation
UNIT 5
Fermentation, Large scale production fermenter design, Study of the production, Blood Products
PHARMACEUTICAL QUALITY ASSURANCE
This course deals with the various aspects of quality control and quality assurance aspects of pharmaceutical industries.
UNIT 1
Quality Assurance and Quality Management concepts, Total Quality Management (TQM), ICH Guidelines, Quality by design (QbD), ISO 9000 and ISO14000, NABL accreditation
UNIT 2
Organization and personnel, Premises, Equipments and raw materials,
UNIT 3
Quality Control and Good Laboratory Practices
UNIT 4
Complaints and document maintenance in pharmaceutical industry
UNIT 5
Calibration and Validation, Warehousing
Bpharm 6th Semester Subject Scope :
Scope of Medicinal Chemistry 3 : This subject is designed to impart fundamental knowledge on the structure, chemistry and therapeutic value of drugs. The subject emphasis on modern techniques of rational drug design like quantitative structure activity relationship (QSAR), Prodrug concept, combinatorial chemistry and Computer aided drug design (CADD). The subject also emphasizes on the chemistry, mechanism of action, metabolism, adverse effects, Structure Activity Relationships (SAR), therapeutic uses and synthesis of important drugs.
Scope of Pharmacology 3 : This subject is intended to impart the fundamental knowledge on various aspects (classification, mechanism of action, therapeutic effects, clinical uses, side effects and contraindications) of drugs acting on respiratory and gastrointestinal system, infectious diseases, immuno-pharmacology and in addition,emphasis on the principles of toxicology and chronopharmacology.
Scope of Herbal Drug Technology : This subject gives the student the knowledge of basic understanding of herbal drug industry, the quality of raw material, guidelines for quality of herbal drugs, herbal cosmetics, natural sweeteners, nutraceutical etc. The subject also emphasizes on Good Manufacturing Practices (GMP), patenting and regulatory issues of herbal drugs.Add Image
Scope of Biopharmaceutics and Pharmacokinetics : This subject is designed to impart knowledge and skills of Biopharmaceutics and pharmacokinetics and their applications in pharmaceutical development, design of dose and dosage regimen and in solving the problems arised therein.Add Image
Scope of Pharmaceutical Biotechnology : has a long promise to revolutionize the biological sciences and technology. Scientific application of biotechnology in the field of genetic engineering, medicine and fermentation technology makes the subject interesting. Biotechnology is leading to new biological revolutions in diagnosis, prevention and cure of diseases, new and cheaper pharmaceutical drugs. Biotechnology has already produced transgenic crops and animals and the future promises lot more. It is basically a research-based subject.Add Image
Scope of Pharmaceutical Quality Assurance : This course deals with the various aspects of quality control and quality assurance aspects of pharmaceutical industries. It deals with the important aspects like cGMP, QC tests, documentation, quality certifications and regulatory affairs.