Bpharm 1st Semester Syllabus – PDF Download (as per PCI)

Bpharm 1st Semester syllabus as per PCI. Download the syllabus and you can also download notes of Bpharm 1st semester.

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Bpharm 1st Semester Syllabus

Introduction to human body
Definition and scope of anatomy and physiology, levels of structural organization and body
systems, basic life processes, homeostasis, basic anatomical terminology.

Cellular level of organization
Structure and functions of cell, transport across cell membrane, cell division, cell junctions.
General principles of cell communication, intracellular signaling pathway activation by
extracellular signal molecule, Forms of intracellular signaling: a) Contact-dependent b) Paracrine
c) Synaptic d) Endocrine

Tissue level of organization
Classification of tissues, structure, location and functions of epithelial, muscular and nervous and
connective tissues.


Integumentary system
Structure and functions of skin

Skeletal system
Divisions of skeletal system, types of bone, salient features and functions of bones of axial and
appendicular skeletal system Organization of skeletal muscle, physiology of muscle contraction,
neuromuscular junction

Joints
Structural and functional classification, types of joints movements and its articulation


Body fluids and blood
Body fluids, composition and functions of blood, hemopoeisis, formation of hemoglobin, anemia,
mechanisms of coagulation, blood grouping, Rh factors, transfusion, its significance and
disorders of blood, Reticulo endothelial system.

Lymphatic system
Lymphatic organs and tissues, lymphatic vessels, lymph circulation and functions of lymphatic
system


Peripheral nervous system
Classification of peripheral nervous system: Structure and functions of sympathetic and
parasympathetic nervous system. Origin and functions of spinal and cranial nerves.

Special senses
Structure and functions of eye, ear, nose and tongue and their disorders.


Cardiovascular system
Heart – anatomy of heart, blood circulation, blood vessels, structure and functions of artery, vein
and capillaries, elements of conduction system of heart and heart beat, its regulation by
autonomic nervous system, cardiac output, cardiac cycle. Regulation of blood pressure, pulse,
electrocardiogram and disorders of heart.


  1. Pharmaceutical analysis
    Definition and scope
    a. Different techniques of analysis
    b. Methods of expressing concentration
    c. Primary and secondary standards.
    d. Preparation and standardization of various molar and normal solutions- Oxalic acid,
    sodium hydroxide, hydrochloric acid, sodium thiosulphate, sulphuric acid, potassium
    permanganate and ceric ammonium sulphate
  2. Errors: Sources of errors, types of errors, methods of minimizing errors, accuracy, precision and
    significant figures
  3. Pharmacopoeia, Sources of impurities in medicinal agents,limit tests.

Acid-base titration: Theories of acid base indicators, classification of acid base titrations and
theory involved in titrations of strong, weak, and very weak acids and bases, neutralization curves

Non aqueous titration: Solvents, acidimetry and alkalimetry titration and estimation of Sodium
benzoate and Ephedrine HCl


Precipitation titrations: Mohr’s method, Volhard’s, Modified Volhard’s, Fajans method, estimation
of sodium chloride.

Complexometric titration: Classification, metal ion indicators, masking and demasking reagents,
estimation of Magnesium sulphate, and calcium gluconate.

Gravimetry: Principle and steps involved in gravimetric analysis. Purity of the precipitate: co
precipitation and post precipitation, Estimation of barium sulphate.
Basic Principles,methods and application of diazotisation titration. Estimation of sodium nitrite
and sodium nitrate.


Redox titrations
a. Concepts of oxidation and reduction
b. Types of redox titrations (Principles and applications)
Cerimetry, Iodimetry, Iodometry, Bromatometry, Dichrometry, Titration with potassium iodate


Electrochemical methods of analysis

Conductometry – Introduction, Conductivity cell, Conductometric titrations, applications.
Potentiometry – Electrochemical cell, construction and working of reference (Standard hydrogen,
silver chloride electrode and calomel electrode) and indicator electrodes (metal electrodes and
glass electrode), methods to determine end point of potentiometric titration and applications.
Polarography – Principle, Ilkovic equation, construction and working of dropping mercury
electrode and rotating platinum electrode, applications.


Historical background and development of profession of pharmacy:
History of profession of Pharmacy in India in relation to pharmacy education, industry and
organization, Pharmacy as a career, Pharmacopoeias: Introduction to IP, BP, USP and Extra
Pharmacopoeia.
Dosage forms: Introduction to dosage forms, classification and definitions
Prescription: Definition, Parts of prescription, handling of Prescription and Errors in prescription.
Posology: Definition, Factors affecting posology. Pediatric dose calculations based on age, body
weight and body surface area.


Pharmaceutical calculations: Weights and measures – Imperial & Metric system, Calculations
involving percentage solutions, alligation, proof spirit and isotonic solutions based on freezing
point and molecular weight.
Powders: Definition, classification, advantages and disadvantages,Simple & compound powders –
official preparations, dusting powders, effervescent, efflorescent and hygroscopic powders,
eutectic mixtures. Geometric dilutions.
Liquid dosage forms: Advantages and disadvantages of liquid dosage forms. Excipients used in
formulation of liquid dosage forms. Solubility enhancement techniques


Monophasic liquids: Definitions and preparations of Gargles, Mouthwashes, Throat Paint,
Eardrops, Nasal drops, Enemas, Syrups, Elixirs, Liniments and Lotions.
Biphasic liquids:
Suspensions: Definition, advantages and disadvantages, classifications, Preparation of
suspensions; Flocculated and Deflocculated suspension & stability problems and methods to
overcome.
Emulsions: Definition, classification, emulsifying agent, test for the identification of type
ofEmulsion, Methods of preparation & stability problems and methods to overcome.


Suppositories: Definition, types, advantages and disadvantages, types of bases, methods of
preparations. Displacement value & its calculations, evaluation of suppositories.
Pharmaceutical incompatibilities: Definition, classification, physical, chemical and therapeutic
incompatibilities with examples.


Semisolid dosage forms: Definitions, classification, mechanisms and factors influencing dermal
penetration of drugs. Preparation of ointments, pastes, creams and gels. Excipients used in semi
solid dosage forms. Evaluation of semi solid dosages forms


Impurities in pharmaceutical substances: History of Pharmacopoeia, Sources and types of
impurities, principle involved in the limit test for Chloride, Sulphate, Iron, Arsenic, Lead and
Heavy metals, modified limit test for Chloride and Sulphate

General methods of preparation, assay for the compounds superscripted with asterisk (*),
properties and medicinal uses of inorganic compounds belonging to the following classes


Acids, Bases and Buffers: Buffer equations and buffer capacity in general, buffers in
pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of
tonicity, calculations and methods of adjusting isotonicity.

Major extra and intracellular electrolytes: Functions of major physiological ions, Electrolytes
used in the replacement therapy: Sodium chloride*, Potassium chloride, Calcium gluconate* and
Oral Rehydration Salt (ORS), Physiological acid base balance.

Dental products: Dentifrices, role of fluoride in the treatment of dental caries, Desensitizing
agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol cement.


Gastrointestinal agents
Acidifiers: Ammonium chloride* and Dil. HCl
Antacid: Ideal properties of antacids, combinations of antacids, Sodium Bicarbonate*, Aluminum
hydroxide gel, Magnesium hydroxide mixture
Cathartics: Magnesium sulphate, Sodium orthophosphate, Kaolin and Bentonite
Antimicrobials: Mechanism, classification, Potassiu permanganate, Boric acid, Hydrogen
peroxide*, Chlorinated lime*, Iodine and its preparations


Miscellaneous compounds
Expectorants: Potassium iodide, Ammonium chloride*.
Emetics: Copper sulphate*, Sodium potassium tartarate
Haematinics: Ferrous sulphate*, Ferrous gluconate
Poison and Antidote: Sodium thiosulphate*, Activated charcoal, Sodium nitrite333
Astringents: Zinc Sulphate, Potash Alum


Radiopharmaceuticals: Radio activity, Measurement of radioactivity, Properties of α, β, γ
radiations, Half life, radio isotopes and study of radio isotopes – Sodium iodide I131, Storage
conditions, precautions & pharmaceutical application of radioactive substances.


Communication Skills: Introduction, Definition, The Importance of Communication, The
Communication Process– Source, Message, Encoding, Channel, Decoding, Receiver,
Feedback, Context
Barriers to communication: Physiological Barriers, Physical Barriers, Cultural Barriers,
Language Barriers, Gender Barriers, Interpersonal Barriers, Psychological Barriers, Emotional
barriers
Perspectives in Communication: Introduction, Visual Perception, Language, Other factors
a ecting our perspective- Past Experiences, Prejudices, Feelings, Environment


Elements of Communication: Introduction, Face to Face Communication- Tone of Voice, Body
Language (Non-verbal communication), Verbal Communication, Physical Communication
Communication Styles: Introduction, The Communication Styles Matrix with example for
each-Direct Communication Style, Spirited Communication Style, Systematic Communication
Style, Considerate Communication Style


Basic Listening Skills: Introduction, Self-Awareness, Active Listening, Becoming an Active
Listener, Listening in Di cult Situations
Effective Written Communication: Introduction, When and When Not to Use Written
Communication- Complexity of the Topic, Amount of Discussion’ Required, Shades of
Meaning, Formal Communication
Writing Effectively: Subject Lines, Put the Main Point First, Know Your Audience, Organization
of the Message


Interview Skills: Purpose of an interview, Do’s and Dont’s of an interview
Giving Presentations: Dealing with Fears, Planning your Presentation, Structuring Your
Presentation, Delivering Your Presentation, Techniques of Delivery


Group Discussion: Introduction, Communication skills in group discussion, Do’s and Dont’s of
group discussion


Living world:
Definition and characters of living organisms
Diversityin the living world
Binomial nomenclature
Five kingdoms of life and basis of classification. Salient features of Monera, Potista, Fungi,
Animalia and Plantae, Virus,
Morphology of Flowering plants
Morphologyof di erent parts of flowering plants– Root, stem, inflorescence, flower, leaf, fruit,
seed.
General Anatomyof Root, stem, leaf of monocotyledons & Dicotylidones.


Body fluids and circulation
Composition of blood, blood groups, coagulation of blood Composition and functions of lymph
Humancirculatorysystem Structure of human heart and blood vessels Cardiac cycle, cardiac output and ECG
Digestion and Absorption
Humanalimentarycanal and digestive glands Role of digestive enzymes Digestion, absorption and assimilation of digested food
Breathing and respiration
Human respiratorysystem Mechanism of breathing and its regulation Exchange of gases, transport of gases and regulation of respiration Respiratoryvolumes


Excretory products and their elimination
Modes of excretion Humanexcretorysystem- structure and function Urine formation
Rennin angiotensin system

Neural control and coordination
Definition and classification of nervous system
Structure of a neuron
Generation and conduction of nerve impulse
Structure of brain and spinal cord
Functions of cerebrum, cerebellum, hypothalamus and medulla oblongata

Chemical coordination and regulation
Endocrine glands and their secretions Functions of hormones secreted byendocrine glands

Human reproduction
Parts of female reproductive system Parts of male reproductive system Spermatogenesis and Oogenesis Menstrual cycle


Plants and mineral nutrition:
Essential mineral, macro and micronutrients
Nitrogen metabolism, Nitrogen cycle, biological nitrogen fixation
Photosynthesis
Autotrophic nutrition, photosynthesis, Photosynthetic pigments, Factors affecting
photosynthesis.


Plant respiration:
Respiration, glycolysis, fermentation (anaerobic).
Plant growth and development
Phases and rate of plant growth, Condition of growth,Introduction to plant growth regulators
Cell– The unit of life
Structure and functions of cell and cell organelles.Cell division
Tissues
Definition, types of tissues, location and functions


Partial fraction
Introduction, Polynomial, Rational fractions, Proper and Improper fractions, Partial fraction ,
Resolving into Partial fraction, Application of Partial Fraction in Chemical Kinetics and
Pharmacokinetics
Logarithms
Introduction, Definition, Theorems/Properties of logarithms, Common logarithms,
Characteristic and Mantissa, worked examples, application of logarithm to solve
pharmaceutical problems.
Function: Real Valued function, Classification of real valued functions,
Limits and continuity :
Introduction, Limit of a function, Definition of limit of a function (ε – δ definition), lim (x → a) (xⁿ – aⁿ) / (x – a) = n aⁿ⁻¹, lim (θ → 0) (sinθ / θ) = 1.


Matrices and Determinant:
Introduction matrices, Types of matrices, Operation on matrices, Transpose of a matrix,
Matrix Multiplication, Determinants, Properties of determinants , Product of determinants,
Minors and co-Factors, Adjoint or adjugate of a square matrix , Singular and non-singular
matrices, Inverse of a matrix, Solution of system of linear of equations using matrix method,
Cramer’s rule, matrix, Characteristic equation and roots of a square Cayley–Hamilton
theorem,Applicationof Matrices in solving Pharmacokinetic equations


Calculus Differentiation: Introductions, Derivative of a function, Derivative of a constant,
Derivative of a product of a constant and a function , Derivative of the sum or di erence of
two functions, Derivative of the product of two functions (product formula), Derivative of the
quotient of two functions (Quotient formula)– Without Proof, Derivative of xn w.r.tx,where n is
any rational number, Derivative of ex,, Derivative of loge x , Derivative of ax ,Derivative of
trigonometric functions from first principles (without Proof), Successive Di erentiation,
Conditions for a function to be a maximum or a minimum at a point. Application


Analytical Geometry
Introduction: Signs of the Coordinates, Distance formula,
Straight Line : Slope or gradient of a straight line, Conditions for parallelism and
perpendicularity of two lines, Slope of a line joining two points, Slope– intercept form of a
straight line
Integration: Introduction, Definition, Standard formulae, Rules of integration , Method of
substitution, Method of Partial fractions, Integration by parts, definite integrals, application


Di erential Equations : Some basic definitions, Order and degree, Equations in separable
form , Homogeneous equations, Linear Di erential equations, Exact equations, Application in
solving Pharmacokinetic equations
Laplace Transform : Introduction, Definition, Properties of Laplace transform, Laplace
Transforms of elementary functions, Inverse Laplace transforms, Laplace transform of
derivatives, Application to solve Linear di erential equations, Application in solving Chemical
kinetics and Pharmacokinetics equations


Download Notes

HUMAN ANATOMY AND PHYSIOLOGY
PHARMACEUTICAL ANALYSIS
PHARMACEUTICS: I
PHARMACEUTICAL INORGANIC CHEMISTRY
COMMUNICATION SKILLS
REMEDIAL BIOLOGY
REMEDIAL MATHEMATICS

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