Pharmaceutical Inorganic Chemistry Notes – 1st Semester

A notebook of Pharmaceutical Inorganic Chemistry

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In this post you can download notes of Pharmaceutical Inorganic Chemistry (BP104T). All units are available to download for free.

Pharmaceutical Inorganic Chemistry Unit 1 – 5

UNIT – 1

Impurities in pharmaceutical substances, General methods of preparation

Limit test of iron

UNIT – 2

Acids, Bases & Buffer, Major extra and intracellular electrolytes, Dental products

Arrhenius Theory

UNIT – 3

Gastrointestinal agents – Acidifiers, Antacid, Cathartics, Antimicrobials

Gastrointestinal agents

UNIT – 4

Miscellaneous compounds – Expectorants, Emetics, Haematinics, Poison and Antidote, Astringents

Expectorants

UNIT – 5

Radiopharmaceuticals

Radio activity

Syllabus of Pharmaceutical Organic Chemistry

UNIT – 1

Impurities in pharmaceutical substances: History of Pharmacopoeia,
Sources and types of impurities, principle involved in the limit test for
Chloride, Sulphate, Iron, Arsenic, Lead and Heavy metals, modified limit test
for Chloride and Sulphate


General methods of preparation, assay for the compounds superscripted
with asterisk (*), properties and medicinal uses of inorganic compounds
belonging to the following classes

UNIT – 2

Acids, Bases and Buffers: Buffer equations and buffer capacity in general,
buffers in pharmaceutical systems, preparation, stability, buffered isotonic
solutions, measurements of tonicity, calculations and methods of adjusting
isotonicity.

Major extra and intracellular electrolytes: Functions of major
physiological ions, Electrolytes used in the replacement therapy: Sodium
chloride, Potassium chloride, Calcium gluconate and Oral Rehydration Salt
(ORS), Physiological acid base balance.

Dental products: Dentifrices, role of fluoride in the treatment of dental
caries, Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc
eugenol cement.

UNIT – 3

Gastrointestinal agents
Acidifiers: Ammonium chloride* and Dil. HCl
Antacid: Ideal properties of antacids, combinations of antacids, Sodium

Gastrointestinal agents
Acidifiers: Ammonium chloride* and Dil. HCl
Antacid: Ideal properties of antacids, combinations of antacids, Sodium

Gastrointestinal agents
Acidifiers: Ammonium chloride* and Dil. HCl
Antacid: Ideal properties of antacids, combinations of antacids, Sodium Bicarbonate*, Aluminum hydroxide gel, Magnesium hydroxide mixture

Cathartics: Magnesium sulphate, Sodium orthophosphate, Kaolin and
Bentonite


Antimicrobials: Mechanism, classification, Potassium permanganate, Boric
acid, Hydrogen peroxide, Chlorinated lime, Iodine and its preparations

UNIT – 4

Miscellaneous compounds


Expectorants: Potassium iodide, Ammonium chloride.

Emetics: Copper sulphate, Sodium potassium tartrate


Haematinics: Ferrous sulphate, Ferrous gluconate

Poison and Antidote: Sodium thiosulphate, Activated charcoal, Sodium
nitrite333


Astringents: Zinc Sulphate, Potash Alum

UNIT – 5

Radiopharmaceuticals: Radio activity, Measurement of radioactivity, Properties of α, β, γ radiations, Half life, radio isotopes and study of radio isotopes – Sodium iodide I131, Storage conditions, precautions & pharmaceutical application of radioactive substances.

Scope of Pharmaceutical Inorganic Chemistry

This subject deals with the monographs of inorganic drugs and pharmaceuticals.

Objectives of Pharmaceutical Inorganic Chemistry

Upon completion of course student shall be able to:

  1. Know the sources of impurities and methods to determine the impurities in inorganic
    drugs and pharmaceuticals.
  2. Understand the medicinal and pharmaceutical importance of inorganic compounds

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